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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EEF1D All Species: 14.24
Human Site: T125 Identified Species: 20.89
UniProt: P29692 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P29692 NP_001951.2 281 31122 T125 S S P G H R A T A P Q T Q H V
Chimpanzee Pan troglodytes XP_512433 281 31148 T125 S S P G H R A T A P Q T Q H V
Rhesus Macaque Macaca mulatta XP_001097290 257 28611 M111 Q T Q H V S P M R Q V E P P A
Dog Lupus familis XP_532345 634 69482 A479 S S P T H R A A A P Q T Q H V
Cat Felis silvestris
Mouse Mus musculus P57776 281 31275 T125 S S P T P R A T A P Q T Q H V
Rat Rattus norvegicus Q68FR9 281 31312 T125 S S P T H R A T A P Q T Q H V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518881 659 71600 P499 S S P S H R S P A P Q T Q H V
Chicken Gallus gallus Q9YGQ1 225 24743 K78 G V K K A L G K Y G P A D V E
Frog Xenopus laevis P29693 265 29219 V119 V A A R V Q K V Q V T P A A K
Zebra Danio Brachydanio rerio XP_002660987 439 49775 S215 T S Q E R D A S A I L Q D I A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VL18 256 28916 N110 E T Q L K L T N G V S K E P E
Honey Bee Apis mellifera XP_392544 267 29648 A121 F V P A D P I A V C P A K P Q
Nematode Worm Caenorhab. elegans P34460 213 22686 R67 A S Y T D A E R K T W A S A G
Sea Urchin Strong. purpuratus XP_780677 279 30452 K124 S S T S A A S K P A T A K P V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84WM9 228 24770 V82 G V R V G G G V A P P S E A H
Baker's Yeast Sacchar. cerevisiae P32471 206 22609 A59 F N H I A S K A D E F D S F P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.7 88.9 40.5 N.A. 92.1 92.5 N.A. 34.4 48.4 61.9 36.2 N.A. 50.1 48.4 41.9 50.1
Protein Similarity: 100 97.1 89.3 42.2 N.A. 94.3 95 N.A. 40 58.7 77.5 49.2 N.A. 64 64 51.9 71.5
P-Site Identity: 100 100 0 86.6 N.A. 86.6 93.3 N.A. 80 0 0 20 N.A. 0 6.6 6.6 20
P-Site Similarity: 100 100 6.6 86.6 N.A. 86.6 93.3 N.A. 86.6 0 13.3 33.3 N.A. 13.3 13.3 13.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. 36.3 35.5 N.A.
Protein Similarity: N.A. N.A. N.A. 51.2 51.2 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 7 7 19 13 38 19 50 7 0 25 7 19 13 % A
% Cys: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % C
% Asp: 0 0 0 0 13 7 0 0 7 0 0 7 13 0 0 % D
% Glu: 7 0 0 7 0 0 7 0 0 7 0 7 13 0 13 % E
% Phe: 13 0 0 0 0 0 0 0 0 0 7 0 0 7 0 % F
% Gly: 13 0 0 13 7 7 13 0 7 7 0 0 0 0 7 % G
% His: 0 0 7 7 32 0 0 0 0 0 0 0 0 38 7 % H
% Ile: 0 0 0 7 0 0 7 0 0 7 0 0 0 7 0 % I
% Lys: 0 0 7 7 7 0 13 13 7 0 0 7 13 0 7 % K
% Leu: 0 0 0 7 0 13 0 0 0 0 7 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 0 0 0 0 7 0 0 0 0 0 0 0 % N
% Pro: 0 0 44 0 7 7 7 7 7 44 19 7 7 25 7 % P
% Gln: 7 0 19 0 0 7 0 0 7 7 38 7 38 0 7 % Q
% Arg: 0 0 7 7 7 38 0 7 7 0 0 0 0 0 0 % R
% Ser: 44 57 0 13 0 13 13 7 0 0 7 7 13 0 0 % S
% Thr: 7 13 7 25 0 0 7 25 0 7 13 38 0 0 0 % T
% Val: 7 19 0 7 13 0 0 13 7 13 7 0 0 7 44 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 0 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _